Effects of chronic stress on dendritic arborization
in the central and extended amygdala
by
Vyas A, Bernal S, Chattarji S.
National Centre for Biological Sciences,
Tata Institute of Fundamental Research,
UAS-GKVK Campus, Bangalore 560065, India.
Brain Res. 2003 Mar 7;965(1-2):290-4.

ABSTRACT

A differential role has been suggested for two important areas in the neural circuitry of stress, central nucleus of the amygdala (CeA) and bed nucleus of stria terminalis (BNST) in the extended amygdala, in regulating fear versus anxiety. Since chronic stress enhances anxiety and consolidation of aversive memories, we examined the effects of chronic immobilization stress (CIS) on neuronal morphology in the CeA and BNST of rats. In contrast to previous reports of stress-induced atrophy in the hippocampus, CIS does not cause dendritic atrophy in CeA and BNST neurons. While dendritic arborization in CeA neurons remains unaffected, it increases in BNST neurons after CIS. These results suggest a role for dendritic remodeling of BNST neurons in stress-induced facilitation of anxiety.

CRF
LHPA
Stress
Cytokines
Antalarmin
Ketoconazole
Noradrenaline
Corticosteroids
Cushing's syndrome
Stress and aggression
Glucocorticoids and mood
Hippocampal remodelling
Neuroendocrinology of stress
Stress, depression and anxiety
HPA axis, serotonin and suicide
Depression, opioids and the HPA
Antidepressants and new brain cells
The corticosteroid hypothesis of depression
An overactive immune system and depression
Stress and CRH, corticosteroids and monoamines
Stress, glucocorticoid receptor loss and depression

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