Anabolic androgenic steroid affects competitive behaviour, behavioural response to ethanol and brain serotonin levels
by
Lindqvist AS, Johansson-Steensland P, Nyberg F, Fahlke C.
Department of Psychology, Goteborg University,
P.O. Box 500, SE-405 30, Goteborg, Sweden
Behav Brain Res 2002 Jun 15;133(1):21-9
ABSTRACTThe present study investigated whether anabolic androgenic steroid (AAS) treatment (daily subcutaneous injections during 2 weeks with nandrolone decanoate; 15 mg/kg) affects competitive behaviour, and locomotor activity response to a sedative dose of ethanol (0.5 g ethanol/kg). In addition, levels of brain monoamines were assessed. The results showed that AAS treated animals exhibited enhanced dominant behaviour in the competition test compared to controls. The AAS groups' locomotor activity was not affected by ethanol in contrast to the controls who showed a sedative locomotor activity. AAS animals had significant lower levels of serotonin in basal forebrain and dorsal striatum compared to controls. These findings further strengthen the fact that AAS affects behaviour, as well as biochemical parameters. Based on previous studies and results from the present study, we hypothesize that AAS abuse may constitute a risk factor for disinhibitory behaviour, partly by affecting the serotonergic system.Nandrolone
DHEA and sex
Neurosteroids
Buprenorphine
New strategies
DHEA: structure
DHEA replacement
Refs
and further readingHOME
HedWeb
Nootropics
cocaine.wiki
Future Opioids
BLTC Research
MDMA/Ecstasy
Superhapiness?
Utopian Surgery?
The Abolitionist Project
The Hedonistic Imperative
The Reproductive Revolution
Critique of Huxley's Brave New World
The Good Drug Guide
The Responsible Parent's Guide
To Healthy Mood Boosters For All The Family
