Relationship between antidepressant partial and nonresponse and subsequent response to antidepressant augmentation
by
Joffe RT, Levitt AJ
Department of Psychiatry,
McMaster University,
Hamilton, ON, Canada.
J Affect Disord 1999 Jan-Mar; 52(1-3):257-9

ABSTRACT

OBJECTIVE: To evaluate the relationship between the degree of antidepressant nonresponse and subsequent response to lithium and triiodothyronine (T3) augmentation. METHOD: This is a retrospective analysis of data combined from two previous controlled studies of lithium and triiodothyronine augmentation of tricyclic antidepressants. RESULTS: There was no difference in the rate of augmentation response between partial and nonresponders to tricyclic antidepressant treatment. CONCLUSIONS: Augmentation response does not appear to be related to the degree of nonresponse to the preceding antidepressant trial.

TCAs
MAOIs
Lithium
T3 v T4
Dysthymia
Anhedonia
Melancholy
Bipolar disorder
Thyroid hormones
Lithium and depression
The thyroid axis and depression

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