Is aspirin, as used for antithrombosis, an emotion-modulating agent?
by
Ketterer MW, Brymer J, Rhoads K, Kraft P, Lovallo WR.
Department of Psychiatry,
Henry Ford Health Sciences Center,
Case Western Reserve University School of Medicine,
Detroit, MI, USA.
J Psychosom Res. 1996 Jan;40(1):53-8

ABSTRACT

Antiplatelet substances, generally aspirin, have become widely used for secondary prevention of ischemic heart disease. Used in relatively small doses, it is generally assumed that aspirin has no psychoactive effect. The present study took advantage of a sample of 174 males undergoing coronary angiography to see if regular aspirin use as prophylactic therapy for ischemic heart disease was associated with one or more of a number of measures of emotional distress. Aspirin use was found to be associated with less depression and anxiety or worry, as reported by the patient and as perceived by a significant other. Despite a significant association of aspirin use with the presence of documented coronary artery disease, the association of aspirin use and diminished distress could not be accounted for by the previously observed high prevalence of depressed/anxious individuals among patients with negative or nominal results on angiography, or by a number of other demographic or clinical variables such as age and socioeconomic status. Although only correlational in nature, present results raise the question of whether aspirin may have a beneficial mood-modulating effect.

Folate
Copper
Vitamin E
Dopamine
Chromium
Natural drugs
Food and mood
Slimming drugs
DL-phenylalanine
Vitamins and mood
Cytokines/depression
Docosahexaenoic acid
Mood, food and cognition
Cytokines and major depression
The Malaise Theory of Depression
Zinc, the NMDA receptor and depression
Folic acid and PUFAs prevent depression and dementia
Caffeine/aspirin combo: effects on mood and performance

Refs
and further reading

HOME
HedWeb
Nootropics
cocaine.wiki
Future Opioids
BLTC Research
MDMA/Ecstasy
Superhapiness?
Utopian Surgery?
The Abolitionist Project
The Hedonistic Imperative
The Reproductive Revolution
Critique of Huxley's Brave New World

The Good Drug Guide
The Responsible Parent's Guide
To Healthy Mood Boosters For All The Family