Subthreshold syndromes of depression
and anxiety in the community
by
Angst J, Merikangas KR, Preisig M
Psychiatric University Hospital Zurich, Switzerland.
J Clin Psychiatry 1997; 58 Suppl 8:6-10

ABSTRACT

Nearly 50% of individuals in the community meet threshold or subthreshold diagnostic criteria for depression or anxiety, with depression being far more common. Co-occurrence of anxiety and depression is common, as the majority of individuals who experience anxiety also manifest threshold- or subthreshold-level depression. In the current study, addition of subthreshold categories improved the coverage of treated cases in the community by nearly a third; 61% of subjects were diagnosed according to threshold criteria while 89% were diagnosed according to subthreshold categories. These results suggest that inclusion of subthreshold-level syndromes enhances the validity of diagnostic systems by increasing the proportion of treated cases that meet diagnostic criteria and by providing a more accurate representation of milder syndromes of depression and anxiety.

TCAs
SSRIs
MAOIs
Dysthymia
Melancholy
Rank theory
Moclobemide
Sedative hypnotics
Drugs for dysthymia
Dysthymia and cyclothymia
Dysthymia: undertreatment
Anxiolytics and antidepressants
Neurobiology and genetics of anxiety
Dysthymia, hyperthymia, cyclothymia
Anxioselective compounds and GABA(A)

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