Clozapine treatment of euphoric mania
by
Antonacci DJ, Swartz CM
Department of Psychiatric Medicine,
East Carolina University School of Medicine,
Greenville, North Carolina 27858-4354, USA.
Ann Clin Psychiatry 1995 Dec; 7(4):203-6

ABSTRACT

Four patients with treatment-resistant euphoric mania characterized by elevated mood, hyperactivity, and rapid speech, refractory to standard treatments and anticonvulsants, showed dramatic improvement in symptoms when treated with clozapine. All developed enhanced functioning and new insight into previous psychopathology. This degree of improvement suggests that clozapine can be considered in the treatment of not only schizophrenia, schizoaffective disorder, and dysphoric mania but also classic euphoric mania unresponsive to traditional treatments.

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